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001) in subjects with hEDS/HSD compared to controls. In addition, significantly more dorsiflexion was found in the medial and lateral forefoot and the rearfoot (p0.001). At the midfoot an increased plantar flexion (p0.001) and at the level of the hallux a decreased dorsiflexion (p=0.037) and increased inversion (p0.001) and abduction (p=0.016) were found in subjects with hEDS/HSD. This study is the first to apply a multi-segment foot model during gait in hEDS/HSD, which confirms the characteristic hypermobility throughout the

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