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ADHD Treatment For Adults - Stimulant Medication Stimulant medicines like methylphenidate or dextroamphetamine are typically considered the as the first line treatment for adults with ADHD. These medications boost and balance brain chemicals called neurotransmitters. Antidepressants and nonstimulant medications, such as atomoxetine, can be prescribed if stimulants aren't appropriate for the patient due to other health issues or adverse