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Intraoperative irrigation with saline-epinephrine solution at a concentration of (1100,00 is safe and does not change heart rate or blood pressure but is unlikely to improve the setting of intraoperative surgical field except for decreasing the volume of blood loss in patients with high Lund-Mackay score. Intraoperative irrigation with saline-epinephrine solution at a concentration of (1100,00 is safe and does not change heart rate or blood pressure but is unlikely to improve the setting of intraoperative surgical field except for d