https://www.selleckchem.com/pr....oducts/Vorinostat-sa
Creatine kinase (CK) activities were elevated (3 times of the upper limit of normal) in eighteen patients, and it was very high (25,000 IU/L) in four patients. Presence of high grade fever, seizures, and high CK activities may be associated with severe SS. Nine patients (16%) received 5-HT2A antagonists as a therapy. About 50% of patients died within 24 h of the onset of symptoms. While fatal SS is rare, frequently observed features include hyperthermia, seizures, and high CK activities. Cyproheptadine use appears infreq
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