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With restricted therapeutic choices, energetic vaccination resistant to the TBE virus (TBEV) is highly recommended in endemic areas. We conduct a systematic evaluation of this medical picture and cerebral imaging findings connected with TBE with particular target clients who obtained TBE despite of past vaccination (vTBE). METHODS We retrospectively describe a cohort of 52 customers with serologically proven TBE managed at our center in a 10-year-period who received one or more cerebral magnetic resonance imag