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More over, the NO amount was reduced, whilst the ET-1 and VEGF levels had been raised under IH condition. These modifications had been suppressed because of the pretreatment of 3-methyladenine.IH upregulates autophagy through AMPK/mTOR pathway in HUVECs in vitro, which might be protective against endothelial apoptosis and dysfunction caused by IH.Prominent spaces exist between technology and rehearse in neuro-scientific nature-based solutions (NBS) internationally, with fairly really formulated ideas but l