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001), and 5-year PFS (HR, 0.70; 95% CI, 0.61-0.79; P0.001) respectively. Besides, subgroup analysis showed that Asian countries have benefited significantly from NAC (HR, 0.65; 95%CI, 0.55-0.74; P0.001), and other countries have also benefited (HR, 0.79; 95%CI, 0.68-0.89; P0.001). Compared with adjuvant chemotherapy and surgery alone, NAC can improve the long-term survival outcomes (OS and PFS) of patients with resectable AGC or EGC. Compared with adjuvant chemotherapy and surgery alone, NAC can improve the long-term surviva