https://www.selleckchem.com/pr....oducts/cepharanthine
Intracellular organelles do not, as thought for a long time, act in isolation but are dynamically tethered together by entire machines responsible for inter-organelle trafficking and positioning. Among the proteins responsible for tethering is the family of vesicle-associated proteins (VAPs) that appear in all eukaryotes and are localized primarily in the endoplasmic reticulum. The major functional role of VAP proteins is to tether the endoplasmic reticulum with different organelles, and regulate lipid metabolism and transport. VA
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