https://www.selleckchem.com/pr....oducts/elimusertib-b
It was reported that carbon monoxide-releasing molecule-3 (CORM-3) administration immediately after hemorrhagic shock and resuscitation (HSR) ameliorates the HSR-induced acute lung injury (ALI); however, the specific mechanism of the protective effects against HSR-induced ALI remains unclear. To induce hemorrhagic shock, rats were bled to a mean arterial blood pressure of 30 mmHg for 45 min and then resuscitated with shed blood via the left vein. CORM-3 (4 or 8 mg/kg) was respectively administrated after HSR. 12 h post-
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