https://www.selleckchem.com/products/n6022.html
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of the motor nervous system. Clinical studies have demonstrated cortical and spinal motor neuron hyperexcitability using transcranial magnetic stimulation and threshold tracking nerve conduction studies, respectively, although metrics of excitability have not been used as pharmacodynamic biomarkers in multi-site clinical trials. To ascertain whether ezogabine decreases cortical and spinal motor neuron excitability in ALS. This double-blind, placebo-controlled p
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