https://p450signals.com/index.....php/prechemoradiothe
We have previously shown that β2AR agonism generates intracellular ROS, an effect that is required for receptor purpose, and which post-translationally oxidizes β2AR cysteine thiols to Cys-S-sulfenic acids (Cys-S-OH). Additionally, extremely oxidative environments can irreversibly oxidize Cys-S-OH to Cys-S-sulfinic (Cys-SO2H) or S-sulfonic (Cys-SO3H) acids, that are incapable of further participating in homeostatic redox reactions (for example., re
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