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OBJECTIVE A growing body of evidence suggests that testing for influenza virus alone is more appropriate than multiplex respiratory viral panel (RVP) testing for general populations of patients with respiratory tract infections. We aimed to decrease the proportion of RVPs out of total respiratory viral testing ordered during influenza season. METHODS We implemented two consecutive interventions reflex testing for RVPs only after a negative influenza test, and noninterruptive clinical decision support (CDS) including modifications of the comp