https://www.selleckchem.com/pr....oducts/pf-04418948.h
Lysine succinylation (Ksucc), defined as a transfer of a succinyl group to a lysine residue of a protein, is a newly identified protein post-translational modification1-3. This chemical modification is reversible, dynamic, and evolutionarily conserved 4 where it has been comprehensively studied in both bacterial and mammalian cells5-7. Numerous proteins involved in the regulation of various cellular and biological processes have been shown to be heavily succinylated5-7. Emerging clinical data provides evidence that dysregulation of
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