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Therefore, understanding the harm due to SARS-COV-2 into the cardiovascular system additionally the underlying components is fundamental. The cardiovascular harm can be related to the instability of the renin-angiotensin-system (RAS) since this virus binds the Angiotensin-Converting-Enzyme 2 (ACE2), expressed regarding the lung alveolar epithelial cells, to come into cells. Virus internalization may cause a downregulation of ACE2 on number mobile surface that may lead to a lo