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Untreated ADHD in Adults Can Lead to Feelings of Worthlessness and Depression Untreated ADHD can result in chronic underachievement and depression. This is particularly true when they fail their professional and personal goals. Diagnoses aren't always easy to determine when there are overlaps in symptoms between ADHD and depression. However, identifying the symptoms is the first step to finding treatment. 1. Feelings of inadequacy Untreated ADHD and co-occurring disorders of depression can cause