https://www.selleckchem.com/pr....oducts/ziftomenib.ht
To investigate the role of CX3CR1 in hyperoxic lung injury induced pulmonary fibrosis. Hyperoxic lung injured mice were used as the disease model. Pulmonary fibrosis was determined by HE and Masson's staining. Autophagy was investigated by western blot, immunofluorescence staining, and transmission electron microscopy. We observed that increased CX3CR1 expression corresponded with increased pulmonary fibrosis. Additionally, silencing of CX3CR1 significantly alleviated the fibrosis when compared to the control. We observed that e
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