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The facile derivatizations and utilizations for the chiral products as novel chiral organocatalysts demonstrate the worthiness of these reactions.Effective treatment of mind metastases is hindered by the blood-brain buffer (BB and the fast improvement weight to drug therapy. Moreover, the medical application of basic formulations is hampered by biological barriers and biological elimination. To handle this challenge, we report a feasible method when it comes to construction of polymer-covalent organic framework

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