https://www.selleckchem.com/products/LBH-589.html
To consider sepsis-induced acute kidney injury, renal functional biomarkers and histopathological changes was assessed. GA treatment significantly improved survival rate at doses of 1, and 2mg/kg. Survival improvement was accompanied by remarkable reduction in the pro-inflammatory cytokines and enhanced production of IL-10. GA showed to have protective effects on renal function as well. Immunomodulatory and anti-inflammatory properties of GA resulted in increase in survival rate and decrease in inflammatory markers in mice model of ceca
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