https://www.selleckchem.com/pr....oducts/muvalaplin.ht
In organisms, activation of mitochondrial unfolded protein response (mt UPR) provides the protective strategy against toxicity of environmental exposures. The aim of this study was to determine the activation of intestinal mt UPR and the underlying mechanisms in nanopolystyrene (100 nm) exposed Caenorhabditis elegans. The exposure was performed from L1-larvae for approximately 6.5-day. Activation of mt UPR as reflected by expressions of both HSP-6GFP and hsp-6 in the intestine could be detected in nanopolystyrene (1-100 μg/L) exposed