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Measurements for the proximal esophageal section included the vigor of contractility associated with the proximal esophagus (proximal contractile integral/PCI). Customers ranked intestinal symptoms' seriousness. Crucial outcomes HREM was carried out on 221 patients (63.8% females, suggest age 57.1 ± 1.1 many years) and 19 HVs. Suggest PCI in HVs was 299.5 ± 30.6 (95% CI 32.3-566.7 mm Hg. s. cm). Of all of the clients, 61 (27.6%) had abnormal PCI. HVs and clients with different esophageal