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To verify the experimental results, Monte Carlo simulations following the experimental set up were performed using Geant4. In addition, analytical calculations for the radiosensitization by GNF were carried out. The confocal Raman spectroscopy on the RCF achieved a spatial resolution of ~6μm. An experimental DEF within the first 6μm depth from the surface of RCF was found to be 17.9 for 50kVp and 14.7 for 120kVp. The DEF for the same depth obtained by MC and analytical calculations was 13.53 and 9.75 for 50kVp, and 10.63 and 6.67 for 12