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The rank of ANA titer for individual ANA patterns observed for each kit was similar to the overall rank of that kit. Variability in ANA titers was strongly associated with the kits used, and the differences between kits were quite consistent during the 11 years studied. Because the variability is not random, it has the potential to be managed by harmonizing kits, which could lead to improved consistency in reporting ANA titers. Variability in ANA titers was strongly associated with the kits used, and the differences between kits were q