https://www.selleckchem.com/pr....oducts/irpagratinib.
(Am J Public Health. Published online ahead of print June 10, 2021 e1-e7. https//doi.org/10.2105/AJPH.2021.3062727).Background Ischemia/reperfusion injury impairs proteostasis, and triggers adaptive cellular responses, such as the unfolded protein response (UPR), which functions to restore endoplasmic reticulum homeostasis. After cardiac arrest (CA) and resuscitation, the UPR is activated in various organs including the brain. However, the role of the UPR in CA has remained largely unknown. Here we aimed to investigate effects of a
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