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4-Methylcyclohexane methanol (MCHM) is a hydrotrope that causes development arrest in fungus. We unearthed that a naturally occurring difference in the Med15 allele, a factor of this Mediator tail, altered the stress reaction to numerous chemical substances as well as MCHM. Med15 includes two polyglutamine repeats (polyQ) of variable lengths that modification the gene expression of diverse paths. The Med15 protein existed in numerous isoforms and its particular stability had been influenced b

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