https://www.selleckchem.com/pr....oducts/Ispinesib-mes
Finally, the liver lipid peroxidation of mice was analyzed. The results of MTT and cell death-defining tests indicate the significant reduction in cell viability and induction of apoptotic death in MCF-7 cells (enhanced sub-G1 peaks, Bax overexpression, Bcl-2 downregulation, and increased apoptotic cells). The antioxidant enzymes (SOD and CAT) in the mice liver and kidney cells were found to be upregulated (p less then .05) in response to the increasing doses of ferutinin. Besides, the lipid peroxidation of the l
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