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Adult ADHD and Comorbid Disorders Many adults with ADHD suffer from comorbid disorders, like major depression (Kessler et al 2006). Many depressed patients do not respond well to medication and may get better results from therapy. Neurotransmitters are brain chemicals that regulate and increase levels of certain brain chemicals. The most commonly prescribed stimulants are amphetamine, methylphenidate, and similar drugs. Medicines Adults can use many drugs that are prescribed for ADHD i