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We used a previously created, data-driven discovery pipeline that requires both semantic annotation and co-occurrence organization analysis to establish a knowledge model. We showed that when compared with hereditary reports, around 56% of testing results are missing or incomplete in the medical records. We built a genetic report knowledge model and highlighted four key semantic groups including "Genes and Gene Products" and "Treatments". Coverage of term annotation had been 99.5%. Accuracies of term annotation an