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Mice by which TonEBP was specifically erased in pancreatic hormonal progenitor cells displayed flawed sugar homeostasis and a loss in islet size. Taken collectively, these conclusions indicate that TonEBP protects against ER stress-induced β-cell death by improving autophagy.Johne's infection (JD) is a life-threatening gastrointestinal infection affecting ruminants, which in turn causes essential affordable losses globally. This ailment is due to Mycobacterium avium subsp.
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