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This study evaluates the distribution of pesticides and assesses the ecological and human health risks associated with pesticide residues concentration in the Thamirabarani River, the only perennial river in Tamil Nadu, India. Observed a variation in the pesticide concentration in the water (not detected (ND)-31.69 μg/L), sediments (ND-14.77 μg/kg), and fish (0.02-26.05 μg/kg). Endosulfan, aldrin, and endrin were the predominant organochlorine pesticides present in water, sediments, and fish. The average concentration of pesticides (exc
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