https://www.selleckchem.com/pr....oducts/m4205-idrx-42
As a result, two novel natural products, an unusual angucyclinone pentangumycin and a new type II polyketide synthase shunt product SEK90, were identified. After purification and structure elucidation, the biosynthetic pathways leading to the formation of pentangumycin and SEK90 were deduced using mutational analysis of the biosynthetic gene cluster and feeding experiments with 13C-labelled precursors. The aim of this study was to measure, at the population level, the prevalence, bother, and treatment-related behavior for lower ur
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