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Average occupancy by olanzapine (10.8 ± 6.0 mg/day) was as follows caudate 32.8 ± 18.3%, putamen 26.3 ± 18.2%, globus pallidus - 33.7 ± 34.9%, substantia nigra - 112.8 ± 90.7%. Average occupancy by blonanserin (12.8 ± 5.6 mg/day) was as follows caudate 61.0 ± 8.3%, putamen 55.5 ± 9.5%, globus pallidus 48.9 ± 12.4%, substantia nigra 34.0 ± 20.6%. EC was 0.30 ng/mL for D receptor for caudate and putamen (df = 19, p 0.0001) and 0.70 ng/mL for D receptor for globus pallidus and substantia nigra (df = 19, p 0.0001). EC for D receptor