https://www.selleckchem.com/pr....oducts/epz015666.htm
Meanwhile, shedding and incomplete cells appeared, of which 900 μmol/L of esculin treatment group showed the most dramatic changes. In addition, the colony formation ratios were decreased to (77.18±5.13)%, (65.94±4.98)% and (45.92±3.7% in the 225, 450 and 900 μmol/L of esculin treatment groups compared with blank control, respectively (P less then 0.01). Furthermore, the mRNA and protein expressions of FBI-1 increased, while the levels of p53 and p21 mRNA and protein, as well as the protein expression of Ki67 decreased in a concentr
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