https://www.selleckchem.com/pr....oducts/k-ras-g12c-in
The clinical syndromes caused by frontotemporal lobar degeneration are heterogeneous, including the behavioural variant frontotemporal dementia (bvFTD) and progressive supranuclear palsy (PSP). Although pathologically distinct, they share many behavioural, cognitive and physiological features, which may in part arise from common deficits of major neurotransmitters such as γ-aminobutyric acid (GABA). Here, we quantify the GABA-ergic impairment and its restoration with dynamic causal modelling of a double-blind placebo-contr