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Treatment of Add Treatment for Add typically involves psychosocial and medication. Treatments for ADHD may include stimulants such as amphetamine and methylphenidate compounds, or non-stimulant medications like atomoxetine (Strattera), bupropion (Wellbutrin) and tricyclic antidepressants. Clonidine, a mood stabilizer, and Guanfacine (Catapres, Kapvay) can be used to treat comorbid mood lability. Stimulants Stimulants stimulate the central nervous system to increase the level of alertness and vigor. can be prescription medications such as amphetamines