https://tastereceptor.com/inde....x.php/within-silico-
In rats, 14-OMeC6SU revealed more powerful antinociceptive effect within the tail-flick assay than codeine and was equipotent to morphine, whereas C6SU was less efficacious after subcutaneous (s.c.) management. After intracerebroventricular shot, 14-OMeC6SU ended up being livlier than morphine. In the perfect Freund's Adjuvant-induced inflammatory hyperalgesia, 14-OMeC6SU and C6SU in s.c. doses up to 6.1 and 13.2 µmol/kg, correspondingly, showed peripheral antihyperalgesic effect, because