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Patients with HPV-positive (HPV+) oropharyngeal squamous cell carcinomas (OPSCCs) are known to have a better prognosis compared to patients with HPV-negative OPSCCs. To investigate the impact of specific HPV genotypes on survival in HPV + OPSCC. A systematic search of PubMed and Embase for studies addressing the association between specific HPV genotypes and survival among patients with OPSCC was performed. Six studies ( = 1385 patients) published between 2013 and 2017 were included. Five studies ( = 1290 patients) found a better sur