https://www.selleckchem.com/pr....oducts/stf-083010.ht
Two metagenomic assemblers, e.g. MEGAHIT and metaSPAdes, performed better compared with others in most of the assembly quality metrics including, recovery of a larger fraction of the genome, constructing larger contigs and higher N50, NA50 values, etc. We showed that at least 09% (259/2873) of the variants present in the assemblies between MEGAHIT and metaSPAdes are unique to one of the assembly methods. Our analyses indicate the critical role of assembly methods for assembling SARS-CoV-2 genome using short reads and their impact on
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