https://www.selleckchem.com/products/r428.html
Moreover, the VDAC1-AKT (protein kinase-GSK3β (glycogen synthase kinase 3 beta)-VDAC1 signaling pathway was abnormally activated in the hippocampus of APP/PS1 mice after noise exposure. Chronic noise exposure and APP/PS1 overexpression may synergistically exacerbate cognitive impairment and neuropathological changes that occur in AD. This interaction may be mediated by the positive feedback loop of the VDAC1-AKT-GSK3β-VDAC1 signaling pathway. Chronic noise exposure and APP/PS1 overexpression may synergistically exacerbate cognitive impai
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