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In this report, a mild and efficient approach to 2-substituted indazolones via B2(OH)4-mediated reductive N-N bond formation is created. This plan features moderate conditions, no ask for a metal catalyst, and an extensive scope for both aliphatic and fragrant amines. Meanwhile, this method was additional successfully applied on DNA to construct indazolone cores for a DNA-encoded library. This may enable the creation of a very attractive indazolone-cored collection from easy amines and scaffolds,

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