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able at 12-month. Moreover, a study with a larger patient population and longer follow-up is warranted to further assess the device. Trial registration Dafodil-1 trial has been prospectively registered on 10/07/2017 under Clinical Trial Registry-India (http//www.ctri.nic.in). (Registration number CTRI/2017/07/009008).Background The mortality rate is very high for patients with severe multiple trauma with massive pulmonary contusion containing intrapulmonary hemorrhage. Multiple treatment modalities are needed not only for a prevention of