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OBJECTIVE The lack of immediate access to a polarized light microscope is often used as an argument to justify the clinical diagnosis of crystal-related arthritis. The aim of this study was to assess the influence of time since sampling and preservation methods on crystal identification in synovial fluid samples under polarized light microscopy. METHODS Prospective, longitudinal, observational factorial study, analyzing 30 synovial fluids samples 12 with monosodium urate crystals (MSU) and 18 with calcium pyrophosphate (CPP) crystals. O

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