https://www.selleckchem.com/products/rp-6685.html
SARS-CoV-2 attacks various organs, most destructively the lung, and cellular entry requires two host cell surface proteins ACE2 and TMPRSS2. Downregulation of one or both of these is thus a potential therapeutic approach for COVID-19. TMPRSS2 is a known target of the androgen receptor, a ligand-activated transcription factor; androgen receptor activation increases TMPRSS2 levels in various tissues, most notably prostate. We show here that treatment with the antiandrogen enzalutamide-a well-tolerated drug widely used in advanced prostate
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