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The segmentation of white blood cells and their nuclei is still difficult and challenging for many reasons, including the differences in their colour, shape, background and staining techniques, the overlapping of cells, and changing cell topologies. This paper shows how these challenges can be addressed by using level set forces via edge-based geometric active contours. In this work, three level set forces-based (curvature, normal direction, and vector field) are comprehensively studied in the context of the problem of segmenting white bl
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