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It was found that the calcium oscillation frequency is upregulated in standard 2D cultures whilst it had been much like in vivo in spheroid and microporous polymer scaffold-based 3D designs, suggesting calcium oscillation frequency as a potential functional CPR signal for neural cultures.Hydrogels tend to be widely used matrices for mesenchymal stem cellular (MSC)-based cartilage regeneration but frequently cause slow cartilage deposition with inferior technical strength. We recently
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