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Echocardiographic studies (n =752) of 102 patients with breast cancer without CTRCD were investigated. The strain analysis showed higher parallel forms, inter-rater, and test-retest reliabilities in patients with CC of A4C 900. During sequential comparisons of automated LVGLS in individual patients, those with CC of A4C 900 had a lower false positive detection rate of CTRCD. CC of A4C was associated with the reliability of automated LVGLS and could also potentially be used as a filter to select comparable images from sequential

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