https://www.selleckchem.com/pr....oducts/chroman-1.htm
Bronchial smooth muscle (BSM) remodelling in asthma is related to an increased mitochondrial biogenesis and enhanced BSM cell proliferation in asthma. Since (i) mitochondria produce the highest levels of cellular energy and (ii) fatty acid beta-oxidation is the most powerful way to produce ATP, we hypothesized that, in asthmatic BSM cells, energetic metabolism is shifted towards the beta-oxidation of fatty acids. We aimed to characterize BSM cell metabolism in asthma both and to identify a novel target for reducing BSM cell proliferat
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