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Furthermore, sesamol supplementation also increased the short-chain fatty acid (SCFAs) contents of acetate, propionate, and butyrate. Additionally, sesamol supplementation changed the gut microbiome construction by boosting the relative abundance of Coprococcuscus, Butyricicoccus, Odoribacter, and AF12 in colitis mice. In closing, sesamol could effectively ameliorate DSS-induced colitis by promoting gut microecology.An computerized online separation and fractiona