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Increasing proof suggests that illness encourages the initiation and development of prostate disease. This research investigated the effects of lipopolysaccharide (LPS), a significant element of Gram-negative bacilli, on proliferation, migration and invasion of prostate cancer cells additionally the safety effects of 1α,25(OH)2D3 (calcitriol). PC-3 and DU145 cells had been stimulated with LPS (2.0 μg/mL) into the presence or lack of 1α,25(OH)2D3 (100 nM). Our outcomes show
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