https://www.selleckchem.com/pr....oducts/cathepsin-Inh
Bayesian analysis demonstrated 1 mg dose obtained the maximum SBMs per week (OR 3.31, 95% credible interval 1.72 to 6.16, probability rank=0.7 indirectly compared with 2 mg and 4 mg doses. TEAEs were higher significantly in 2 mg (risk ratio (RR) 1.20, 95% CI 1.09 to 1.33) and 4 mg (RR 1.14, 95% CI 1.07 to 1.22) prucalopride. The 1 mg dose did not reach statistical significance (RR 1.17, 95% CI 0.94 to 1.44). The study concludes that 1 mg dose at commencement could be safer in treating CIC and that 2 mg prucalopride could
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