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olic biomarkers, indicative of the activity and spread of bone metastases from prostate cancer.Stroke is one of the leading causes of mortality and morbidity worldwide. The blood-brain barrier (BB is a characteristic structure of microvessel within the brain. Under normal physiological conditions, the BBB plays a role in the prevention of harmful substances entering into the brain parenchyma within the central nervous system. However, stroke stimuli induce the breakdown of BBB leading to the influx of cytotoxic substances, vasogenic b

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